P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities. [electronic resource]
Producer: 19950222Description: 1643-9 p. digitalISSN:- 0021-9258
- Adrenal Glands -- enzymology
- Aging -- metabolism
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Cytochrome P-450 CYP11B2
- Cytochrome P-450 Enzyme System -- biosynthesis
- DNA Primers
- DNA, Complementary
- Embryonic and Fetal Development
- Female
- Fetus
- Gene Expression Regulation, Enzymologic
- In Situ Hybridization
- Male
- Molecular Sequence Data
- Oligonucleotides, Antisense
- Organ Specificity
- Polymerase Chain Reaction
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley -- genetics
- Restriction Mapping
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Sex Characteristics
- Sex Factors
- Steroid 11-beta-Hydroxylase -- biosynthesis
- Substrate Specificity
- Transcription, Genetic
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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