Effect of dexamethasone treatment on the biotransformation of glyceryl trinitrate: cytochrome P450 3A1 mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate. [electronic resource]
Producer: 19950607Description: 1513-20 p. digitalISSN:- 0008-4212
- Animals
- Aorta -- drug effects
- Aryl Hydrocarbon Hydroxylases
- Biotransformation
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- drug effects
- Dexamethasone -- pharmacology
- Enzyme Activation
- Female
- Guanylate Cyclase -- drug effects
- In Vitro Techniques
- Male
- Microsomes, Liver -- drug effects
- Mixed Function Oxygenases -- drug effects
- Nitroglycerin -- metabolism
- Rats
- Rats, Sprague-Dawley
- Vasoconstriction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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