Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo. [electronic resource]
Producer: 19950509Description: 1418-25 p. digitalISSN:- 1046-6673
- Animals
- Antibody Formation -- drug effects
- Colchicine -- pharmacology
- Cytokines -- metabolism
- Graft Survival -- drug effects
- Immune System -- drug effects
- Isoantigens -- immunology
- Kidney Transplantation
- Lymphocyte Culture Test, Mixed
- Male
- Microtubules -- drug effects
- Rats
- Rats, Inbred BN
- Rats, Inbred Lew
- T-Lymphocytes, Cytotoxic -- cytology
- T-Lymphocytes, Regulatory -- drug effects
- Th1 Cells -- physiology
- Th2 Cells -- physiology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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