Use of human organ slices to evaluate the biotransformation and drug-induced side-effects of pharmaceuticals. [electronic resource]
Producer: 19950504Description: 407-14 p. digitalISSN:- 0742-2091
- Animals
- Aryl Hydrocarbon Hydroxylases
- Biotransformation
- Cell Survival -- drug effects
- Cyclosporine -- chemistry
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- metabolism
- Glutathione Transferase -- metabolism
- Humans
- Kidney -- drug effects
- Lipoprotein(a) -- metabolism
- Liver -- drug effects
- Nuclear Proteins -- metabolism
- Organ Culture Techniques
- Oxidoreductases, N-Demethylating -- metabolism
- Polyenes -- pharmacology
- Rats
- Sirolimus
- Toxicity Tests -- methods
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Publication Type: Journal Article
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