Generation of amyloid beta protein from its precursor is sequence specific. [electronic resource]
Producer: 19950501Description: 661-70 p. digitalISSN:- 0896-6273
- Alzheimer Disease -- genetics
- Amino Acid Sequence
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides -- biosynthesis
- Amyloid beta-Protein Precursor -- chemistry
- Aspartic Acid Endopeptidases
- Base Sequence
- Brain -- metabolism
- Cell Line
- Endopeptidases -- metabolism
- Humans
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Neuroblastoma
- Oligodeoxyribonucleotides
- Point Mutation
- Protein Processing, Post-Translational
- Substrate Specificity
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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