Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase. [electronic resource]
Producer: 19930713Description: 12818-24 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Animals
- Base Sequence
- Carcinoma, Hepatocellular
- Cell Division
- Cloning, Molecular
- DNA, Neoplasm
- Farnesyl-Diphosphate Farnesyltransferase -- biosynthesis
- Gene Expression Regulation, Enzymologic -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Hydroxycholesterols -- pharmacology
- Hydroxymethylglutaryl CoA Reductases -- biosynthesis
- Kinetics
- Liver -- enzymology
- Liver Neoplasms
- Lovastatin -- pharmacology
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- RNA -- isolation & purification
- RNA, Messenger -- metabolism
- Rats
- Sequence Homology, Amino Acid
- Transcription, Genetic -- drug effects
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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