N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions. [electronic resource]
Producer: 19950905Description: 18013-8 p. digitalISSN:- 0021-9258
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA
- Humans
- Insulin-Like Growth Factor II -- genetics
- Leucine -- genetics
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Protein Binding
- Receptor, IGF Type 1 -- metabolism
- Receptor, Insulin -- metabolism
- Sequence Deletion
- Threonine -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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