Inhibition of protein kinase C, but not of protein kinase A, blocks the development of acute antinociceptive tolerance to an intrathecally administered mu-opioid receptor agonist in the mouse. [electronic resource]
Producer: 19951207Description: R1-3 p. digitalISSN:- 0014-2999
- Analgesics -- pharmacology
- Animals
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- Dose-Response Relationship, Drug
- Drug Tolerance
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
- Enkephalins -- pharmacology
- Injections, Spinal
- Male
- Mice
- Mice, Inbred ICR
- Protein Kinase C -- antagonists & inhibitors
- Receptors, Opioid, mu -- agonists
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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