scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase. [electronic resource]
Producer: 19951025Description: 5700-6 p. digitalISSN:- 0270-7306
- Animals
- Antigens, Nuclear
- B-Lymphocytes
- Cell Extracts
- Cell Line
- Cell Line, Transformed
- Chromosomes, Human, Pair 8
- DNA -- metabolism
- DNA Helicases
- DNA Repair
- DNA-Activated Protein Kinase
- DNA-Binding Proteins -- metabolism
- Fibroblasts
- Gamma Rays
- Genetic Complementation Test
- Humans
- Ku Autoantigen
- Mice
- Mice, SCID
- Nuclear Proteins -- metabolism
- Phosphorylation -- radiation effects
- Protein Serine-Threonine Kinases -- metabolism
- Recombination, Genetic
- Replication Protein A
- Severe Combined Immunodeficiency -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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