Point mutations in the conserved box 1 region inactivate the human granulocyte colony-stimulating factor receptor for growth signal transduction and tyrosine phosphorylation of p75c-rel. [electronic resource]
Producer: 19950623Description: 3117-26 p. digitalISSN:- 0006-4971
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Division
- Cell Line -- drug effects
- DNA, Complementary -- genetics
- Enzyme Activation
- Granulocyte Colony-Stimulating Factor -- metabolism
- Hematopoietic Stem Cells -- drug effects
- Humans
- Interleukin-3 -- pharmacology
- Mice
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phosphorylation -- drug effects
- Point Mutation
- Protein Processing, Post-Translational -- drug effects
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-rel
- Receptor Protein-Tyrosine Kinases -- genetics
- Receptors, Granulocyte Colony-Stimulating Factor -- genetics
- Recombinant Fusion Proteins -- genetics
- Regulatory Sequences, Nucleic Acid
- Signal Transduction -- drug effects
- Transfection
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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