Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase. [electronic resource]
Producer: 19950531Description: 831-42 p. digitalISSN:- 0021-9525
- Actin Cytoskeleton -- physiology
- Actins -- metabolism
- Avian Proteins
- Biological Transport
- Blood Platelets -- drug effects
- Cell Adhesion Molecules -- metabolism
- Cell Compartmentation
- Cytoskeletal Proteins -- metabolism
- Cytoskeleton -- physiology
- Enzyme Activation
- Focal Adhesion Kinase 1
- Focal Adhesion Protein-Tyrosine Kinases
- Humans
- Integrins -- metabolism
- Multienzyme Complexes -- metabolism
- Phosphatidylinositol 3-Kinases
- Phosphorylation
- Phosphotransferases (Alcohol Group Acceptor) -- metabolism
- Platelet Activation -- physiology
- Platelet Glycoprotein GPIIb-IIIa Complex
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins pp60(c-src) -- metabolism
- Signal Transduction -- physiology
- Thrombin -- pharmacology
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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