Synthesis and biological evaluation of NK1 antagonists derived from L-tryptophan. [electronic resource]
Producer: 19950428Description: 934-41 p. digitalISSN:- 0022-2623
- Amines -- metabolism
- Amino Acid Sequence
- Animals
- Binding Sites
- Biphenyl Compounds -- chemical synthesis
- CHO Cells
- Cardiovascular System -- drug effects
- Cricetinae
- Esters -- chemical synthesis
- Extravasation of Diagnostic and Therapeutic Materials -- drug therapy
- Female
- Ferrets
- Guinea Pigs
- Heterocyclic Compounds -- chemical synthesis
- Humans
- Hypnotics and Sedatives -- metabolism
- Male
- Molecular Sequence Data
- Neurokinin-1 Receptor Antagonists
- Piperidines -- chemical synthesis
- Receptors, Neurokinin-1 -- metabolism
- Solubility
- Structure-Activity Relationship
- Substance P -- antagonists & inhibitors
- Tryptophan -- analogs & derivatives
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Publication Type: Comparative Study; Journal Article
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