A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease. [electronic resource]
Producer: 19951207Description: 113-20 p. digitalISSN:- 0083-8969
- Alzheimer Disease -- metabolism
- Amyloid beta-Peptides -- toxicity
- Animals
- Creatine Kinase -- antagonists & inhibitors
- Electron Spin Resonance Spectroscopy
- Free Radicals
- Gerbillinae
- Glutamate-Ammonia Ligase -- antagonists & inhibitors
- Humans
- Hydroxylation
- In Vitro Techniques
- Lipid Peroxidation -- drug effects
- Male
- Neurons -- drug effects
- Neurotoxins -- toxicity
- Salicylates -- metabolism
- Spin Labels
- Synaptosomes -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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