Synthesis and evaluation of novel N-substituted N'-(3-hydroxy-17-oxoestra-1,3,5(10)-trien-2- and -4-yl)thiourea derivatives for binding to the estrogen receptor and cytotoxic activity on MCF-7 cells. [electronic resource]
Producer: 19850410Description: 1871-3 p. digitalISSN:- 0022-3549
- Animals
- Antineoplastic Agents -- chemical synthesis
- Breast Neoplasms -- pathology
- Cell Division -- drug effects
- Cell Line
- Chemical Phenomena
- Chemistry
- Estrenes -- chemical synthesis
- Estrogen Antagonists -- chemical synthesis
- Female
- Humans
- In Vitro Techniques
- Rats
- Receptors, Estrogen -- metabolism
- Thiourea -- analogs & derivatives
- Uterus -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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