The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins. [electronic resource]
Producer: 19860116Description: 1099-106 p. digitalISSN:- 0277-5379
- Animals
- Ascorbic Acid -- pharmacology
- Biotransformation -- drug effects
- Cytochrome P-450 Enzyme System -- pharmacology
- Etoposide -- metabolism
- HeLa Cells -- metabolism
- Humans
- In Vitro Techniques
- Microsomes -- metabolism
- Microsomes, Liver -- metabolism
- NADP
- Neoplasm Proteins -- metabolism
- Nitrogen Oxides -- pharmacology
- Phenobarbital -- pharmacology
- Podophyllotoxin -- analogs & derivatives
- Proadifen -- pharmacology
- Protein Binding
- Pyridines
- Rats
- Rats, Inbred Strains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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