A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717. [electronic resource]
Producer: 19860917Description: 1245-52 p. digitalISSN:- 0732-183X
- Acetylglucosaminidase -- urine
- Acid Phosphatase -- blood
- Alanine Transaminase -- blood
- Antineoplastic Agents -- administration & dosage
- Chemical and Drug Induced Liver Injury
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Drug Evaluation
- Folic Acid -- analogs & derivatives
- Folic Acid Antagonists -- administration & dosage
- Glomerular Filtration Rate -- drug effects
- Hematologic Diseases -- chemically induced
- Hyperbilirubinemia -- chemically induced
- Kidney Diseases -- chemically induced
- Leucyl Aminopeptidase -- urine
- Neoplasms -- blood
- Quinazolines -- administration & dosage
- Skin Diseases -- chemically induced
- Thymidylate Synthase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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