Isolation, synthesis, and antitumor evaluation of spirohydantoin aziridine, a mutagenic metabolite of spirohydantoin mustard. [electronic resource]
Producer: 19870311Description: 1319-21 p. digitalISSN:- 0022-2623
- Animals
- Antineoplastic Agents -- chemical synthesis
- Aziridines -- chemical synthesis
- Azirines -- chemical synthesis
- Biotransformation
- Drug Evaluation, Preclinical
- Leukemia P388 -- drug therapy
- Mice
- Microsomes, Liver -- metabolism
- Mutagenicity Tests
- Mutagens -- chemical synthesis
- Mutation
- Salmonella typhimurium -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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