Oxidative metabolism of the carcinogen 6-fluorobenzo[c]phenanthrene. Effect of a K-region fluoro substituent on the regioselectivity of cytochromes P-450 in liver microsomes from control and induced rats. [electronic resource]
Producer: 19880414Description: 3676-83 p. digitalISSN:- 0021-9258
- Animals
- Binding Sites
- Carcinogens -- metabolism
- Cytochrome P-450 Enzyme System -- metabolism
- Hydrocarbons, Fluorinated -- metabolism
- Magnetic Resonance Spectroscopy -- methods
- Male
- Methylcholanthrene -- pharmacology
- Microsomes, Liver -- drug effects
- Molecular Conformation
- Oxidation-Reduction
- Phenanthrenes -- metabolism
- Phenobarbital -- pharmacology
- Protein Binding
- Rats
- Reference Values
- Structure-Activity Relationship
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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