Cytotoxicity, mutations and SCEs induced by methylating agents are reduced in CHO cells expressing an active mammalian O6-methylguanine-DNA methyltransferase gene. [electronic resource]
Producer: 19871105Description: 1417-21 p. digitalISSN:- 0143-3334
- 4-Nitroquinoline-1-oxide -- pharmacology
- Alkylation
- Animals
- Cell Survival
- Cells, Cultured
- Cricetinae
- Cricetulus
- DNA -- drug effects
- Dose-Response Relationship, Drug
- Guanine -- analogs & derivatives
- Methylation
- Methylnitronitrosoguanidine -- pharmacology
- Methylnitrosourea -- pharmacology
- Mutation
- Ouabain -- pharmacology
- Sister Chromatid Exchange -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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