Selective targeting of PI3Kδ suppresses human IL-17-producing T cells and innate-like lymphocytes and may be therapeutic for IL-17-mediated diseases. [electronic resource]
Producer: 20210830Description: 102435 p. digitalISSN:- 1095-9157
- Anti-Inflammatory Agents -- pharmacology
- Cells, Cultured
- Class I Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
- Female
- Fibroblasts -- physiology
- Humans
- Immunity, Innate
- Interleukin-17 -- metabolism
- Lymphocytes -- immunology
- Male
- Middle Aged
- Osteogenesis
- Psoriasis -- immunology
- Pyridines -- pharmacology
- Quinolines -- pharmacology
- Spondylitis, Ankylosing -- immunology
- Synoviocytes -- physiology
- Th17 Cells -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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