LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. [electronic resource]
Producer: 20200729Description: 2082 p. digitalISSN:- 2041-1723
- Adult
- Animals
- Base Sequence
- Cell Differentiation -- drug effects
- Endocrine Cells -- cytology
- Enhancer Elements, Genetic -- genetics
- Female
- Gene Expression Regulation, Developmental -- drug effects
- Gene Silencing -- drug effects
- Histone Demethylases -- metabolism
- Human Embryonic Stem Cells -- cytology
- Humans
- Islets of Langerhans -- cytology
- Male
- Mice
- Signal Transduction -- drug effects
- Transcription Factors -- metabolism
- Tretinoin -- metabolism
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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