Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- [electronic resource]
Producer: 20210510ISSN:- 2053-8790
- Animals
- Autoantibodies -- metabolism
- Disease Models, Animal
- Extracellular Traps -- immunology
- Female
- Humans
- Interferon Type I -- immunology
- Kidney -- metabolism
- Kidney Diseases -- metabolism
- Lupus Erythematosus, Systemic -- immunology
- Male
- Mice
- Mice, Inbred MRL lpr
- Mitochondria -- metabolism
- Neutrophils -- immunology
- Organophosphorus Compounds -- pharmacology
- Oxidation-Reduction -- drug effects
- Oxidative Stress -- immunology
- Reactive Oxygen Species -- metabolism
- T-Lymphocytes -- immunology
- Ubiquinone -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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