Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease. [electronic resource]
Producer: 20210302Description: 103844 p. digitalISSN:- 1090-2120
- Alzheimer Disease -- drug therapy
- Amyloid beta-Peptides -- antagonists & inhibitors
- Animals
- Carbolines -- chemistry
- Cell Survival -- drug effects
- Cinnamates -- chemistry
- Dose-Response Relationship, Drug
- Drug Design
- Humans
- Male
- Maze Learning -- drug effects
- Mice
- Mice, Inbred ICR
- Molecular Structure
- Neuroprotective Agents -- chemical synthesis
- Peptide Fragments -- antagonists & inhibitors
- Protein Aggregates -- drug effects
- Rats
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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