Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition. [electronic resource]
Producer: 20200804Description: 1897 p. digitalISSN:- 2041-1723
- Adult
- Aged
- Aged, 80 and over
- Cell Differentiation
- Cell Line, Tumor
- Down-Regulation
- Drug Resistance, Neoplasm -- genetics
- Female
- Gene Expression Regulation, Neoplastic
- Histocompatibility Antigens Class I -- genetics
- Humans
- Immunotherapy
- Male
- Melanoma -- genetics
- Middle Aged
- Programmed Cell Death 1 Receptor -- drug effects
- Transcriptome
- Tumor Microenvironment -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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