Myotonic Dystrophy type 1 cells display impaired metabolism and mitochondrial dysfunction that are reversed by metformin. [electronic resource]
Producer: 20210225Description: 6260-6275 p. digitalISSN:- 1945-4589
- Adult
- Aged
- Energy Metabolism -- drug effects
- Female
- Fibroblasts -- metabolism
- Humans
- Hypoglycemic Agents -- administration & dosage
- Leukocytes, Mononuclear -- metabolism
- Male
- Metformin -- administration & dosage
- Mitochondria -- metabolism
- Mitochondrial Diseases -- drug therapy
- Myotonic Dystrophy -- blood
- Oxidative Phosphorylation -- drug effects
- Oxygen Consumption -- drug effects
- Reactive Oxygen Species -- analysis
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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