A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation. [electronic resource]
Producer: 20210513Description: 4749-4761 p. digitalISSN:- 1838-7640
- Acute Lung Injury -- chemically induced
- Animals
- Cells, Cultured
- Cyclooxygenase 2 -- chemistry
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Epoxide Hydrolases -- antagonists & inhibitors
- Inflammasomes -- drug effects
- Lipopolysaccharides -- pharmacology
- Lung -- drug effects
- Macrophages -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- NLR Family, Pyrin Domain-Containing 3 Protein -- antagonists & inhibitors
- Oxidative Stress
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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