Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. [electronic resource]
Producer: 20201201Description: 113980 p. digitalISSN:- 1873-2968
- Acetylcholinesterase -- chemistry
- Binding Sites
- Cathepsin A -- antagonists & inhibitors
- Cell Line
- Chemical Warfare Agents -- chemistry
- Cholinesterase Inhibitors -- chemistry
- Crystallography, X-Ray
- GPI-Linked Proteins -- antagonists & inhibitors
- Gene Expression
- HEK293 Cells
- Humans
- Isoflurophate -- chemistry
- Kinetics
- Models, Molecular
- Organophosphorus Compounds -- chemistry
- Organothiophosphorus Compounds -- chemistry
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Recombinant Proteins -- chemistry
- Sarin -- chemistry
- Soman -- chemistry
- Substrate Specificity
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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