Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities. [electronic resource]
Producer: 20201102Description: 4790-4810 p. digitalISSN:- 1520-4804
- Animals
- Anti-HIV Agents -- chemical synthesis
- Capsid Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Drug Design
- Female
- HIV-1 -- chemistry
- HIV-2 -- chemistry
- Humans
- Male
- Mice
- Microsomes, Liver -- metabolism
- Molecular Structure
- Phenylalanine -- analogs & derivatives
- Rats, Sprague-Dawley
- Structure-Activity Relationship
- Sulfonamides -- chemical synthesis
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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