NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2 [electronic resource]
Producer: 20211007Description: 5 p. digitalISSN:- 2059-3635
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Insulin Receptor Substrate Proteins -- antagonists & inhibitors
- Janus Kinase 2 -- genetics
- Myeloproliferative Disorders -- drug therapy
- Polycythemia Vera -- drug therapy
- Pyrogallol -- analogs & derivatives
- STAT3 Transcription Factor -- antagonists & inhibitors
- STAT5 Transcription Factor -- antagonists & inhibitors
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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