Combined inhibition of Notch and FLT3 produces synergistic cytotoxic effects in FLT3/ITD [electronic resource]
Producer: 20211007Description: 21 p. digitalISSN:- 2059-3635
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Genes, Duplicate -- genetics
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mutation
- Niacinamide -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Receptors, CXCR3 -- genetics
- Signal Transduction -- drug effects
- Sorafenib -- pharmacology
- Tandem Repeat Sequences -- genetics
- Xenograft Model Antitumor Assays
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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