Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors. [electronic resource]
Producer: 20210430Description: 127170 p. digitalISSN:- 1464-3405
- Amides -- chemistry
- Binding Sites
- Enzyme Inhibitors -- chemical synthesis
- Heterocyclic Compounds -- chemistry
- Humans
- Kinetics
- Molecular Docking Simulation
- Protein Tyrosine Phosphatase, Non-Receptor Type 1 -- antagonists & inhibitors
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- antagonists & inhibitors
- Structure-Activity Relationship
- src Homology Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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