Glycemic control with insulin attenuates sepsis-associated encephalopathy by inhibiting glial activation via the suppression of the nuclear factor kappa B and mitogen-activated protein kinase signaling pathways in septic rats. [electronic resource]
Producer: 20210730Description: 146822 p. digitalISSN:- 1872-6240
- Animals
- Blood Glucose -- metabolism
- Brain Diseases -- drug therapy
- Disease Models, Animal
- Glycemic Control -- methods
- Hyperglycemia -- metabolism
- Insulin -- metabolism
- MAP Kinase Signaling System
- Male
- Mitogen-Activated Protein Kinases -- metabolism
- NF-kappa B -- metabolism
- Neuroglia -- metabolism
- Rats
- Rats, Sprague-Dawley
- Sepsis -- complications
- Sepsis-Associated Encephalopathy -- drug therapy
- Signal Transduction -- physiology
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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