A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology. [electronic resource]
Producer: 20200706Description: e0226661 p. digitalISSN:- 1932-6203
- Adaptive Immunity -- drug effects
- Aminoacyltransferases -- antagonists & inhibitors
- Antigens, Differentiation -- chemistry
- CD47 Antigen -- chemistry
- Drug Development
- Gene Expression Regulation, Neoplastic -- drug effects
- High-Throughput Screening Assays -- methods
- Humans
- Immunotherapy -- methods
- Jurkat Cells
- Laser Scanning Cytometry
- Ligands
- Medical Oncology -- trends
- Neoplasms -- drug therapy
- Phagocytosis -- drug effects
- Protein Interaction Maps -- genetics
- Receptors, Immunologic -- chemistry
- Small Molecule Libraries -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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