Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy. [electronic resource]
Producer: 20210517ISSN:- 2379-3708
- Animals
- Antineoplastic Agents -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols
- Carcinoma, Pancreatic Ductal
- Drug Evaluation, Preclinical
- Drug Resistance, Neoplasm -- drug effects
- Fluorouracil -- pharmacology
- Humans
- Leucovorin
- MAP Kinase Kinase 4 -- antagonists & inhibitors
- Mice
- Mitogen-Activated Protein Kinase 8 -- antagonists & inhibitors
- Organoplatinum Compounds
- Pancreatic Neoplasms
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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