Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer's agent. [electronic resource]
Producer: 20210112Description: 173065 p. digitalISSN:- 1879-0712
- Alzheimer Disease -- drug therapy
- Amyloid -- metabolism
- Amyloid beta-Peptides -- metabolism
- Animals
- Computer Simulation
- Disease Models, Animal
- Glycogen Synthase Kinase 3 beta -- metabolism
- Male
- Maze Learning -- drug effects
- Molecular Dynamics Simulation
- Neuroprotective Agents -- pharmacology
- PC12 Cells
- Peptide Fragments -- metabolism
- Protein Aggregation, Pathological -- metabolism
- Protein Binding
- Rats
- Rats, Sprague-Dawley
- Tacrine -- analogs & derivatives
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Publication Type: Journal Article
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