PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest [electronic resource]
Producer: 20210208Description: 167-176 p. digitalISSN:- 1308-5263
- Aminopyridines -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Morpholines -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors -- pharmacology
- Structure-Activity Relationship
- Tumor Cells, Cultured
- U937 Cells
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Publication Type: Journal Article
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