Helveticoside Exhibited p53-dependent Anticancer Activity Against Colorectal Cancer. [electronic resource]
Producer: 20200921Description: 224-232 p. digitalISSN:- 1873-5487
- Animals
- Antineoplastic Agents -- adverse effects
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Caspase 9 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colorectal Neoplasms -- drug therapy
- Digitalis Glycosides -- adverse effects
- HCT116 Cells
- Humans
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Nude
- Mice, SCID
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Strophanthins -- adverse effects
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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