Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas. [electronic resource]
Producer: 20200810Description: 308-323.e12 p. digitalISSN:- 1878-3686
- Activin Receptors, Type I -- antagonists & inhibitors
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Bone Morphogenetic Proteins -- genetics
- Brain Neoplasms -- drug therapy
- Cell Differentiation -- genetics
- Cell Line, Tumor
- Class I Phosphatidylinositol 3-Kinases -- genetics
- Female
- Glioma -- drug therapy
- Histones -- genetics
- Humans
- Lactones -- pharmacology
- Male
- Mice, Transgenic
- Mutation
- Neoplasms, Experimental -- genetics
- Neuroglia -- metabolism
- Oligodendroglia -- pathology
- Receptor, Platelet-Derived Growth Factor alpha -- genetics
- SOXC Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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