The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice. [electronic resource]
Producer: 20200717Description: 489-494 p. digitalISSN:- 1549-5477
- Animals
- Biphenyl Compounds -- pharmacology
- Cells, Cultured
- Cellular Senescence -- drug effects
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Female
- Gene Expression Regulation -- drug effects
- Liver -- physiology
- Male
- Mice
- Mice, Inbred C57BL
- Models, Animal
- Nitrophenols -- pharmacology
- Piperazines -- pharmacology
- Regeneration -- drug effects
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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