A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets. [electronic resource]
Producer: 20200713Description: 6103-6113 p. digitalISSN:- 1091-6490
- Aminopyridines -- pharmacology
- Animals
- Biomarkers, Tumor -- antagonists & inhibitors
- Carcinoma, Hepatocellular -- genetics
- Cell Differentiation -- drug effects
- Cell Line
- Cell Transformation, Neoplastic -- drug effects
- Cohort Studies
- Disease-Free Survival
- E2F1 Transcription Factor -- antagonists & inhibitors
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Neoplastic
- Hepatectomy
- Hepatocytes -- pathology
- Human Embryonic Stem Cells
- Humans
- Hydroxyquinolines -- pharmacology
- Isoquinolines -- pharmacology
- Kaplan-Meier Estimate
- Liver -- growth & development
- Liver Neoplasms -- genetics
- Male
- Mice
- Middle Aged
- Prognosis
- Pyridines -- pharmacology
- Pyrroles -- pharmacology
- Signal Transduction -- genetics
- Smad3 Protein -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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