β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression. [electronic resource]
Producer: 20200803Description: 153183 p. digitalISSN:- 1618-095X
- Activating Transcription Factor 4 -- metabolism
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacokinetics
- Apoptosis -- drug effects
- Bone Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Endoplasmic Reticulum Stress -- drug effects
- Eukaryotic Initiation Factor-2 -- metabolism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Male
- Mice, Inbred BALB C
- Osteosarcoma -- drug therapy
- Phenanthrenes -- pharmacology
- Tissue Distribution
- Transcription Factor CHOP -- genetics
- Triterpenes
- Wnt Signaling Pathway -- drug effects
- Xenograft Model Antitumor Assays
- beta Catenin -- metabolism
- eIF-2 Kinase -- metabolism
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.