Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies. [electronic resource]
Producer: 20201112Description: 3080 p. digitalISSN:- 2045-2322
- Adult
- Aged
- Angiogenesis Inhibitors -- adverse effects
- Boron Compounds -- adverse effects
- Glycine -- adverse effects
- Humans
- Indazoles
- Kaplan-Meier Estimate
- Middle Aged
- Mutation -- genetics
- Neoplasms -- drug therapy
- Progression-Free Survival
- Pyrimidines -- adverse effects
- Sulfonamides -- adverse effects
- Treatment Outcome
- Tumor Suppressor Protein p53 -- genetics
- Vorinostat -- adverse effects
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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