An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. [electronic resource]
Producer: 20200323Description: 428-440.e9 p. digitalISSN:- 1934-6069
- Amino Acid Sequence
- Animals
- Binding Sites
- Cattle -- genetics
- Chikungunya Fever -- genetics
- Chikungunya virus
- Chlorocebus aethiops
- Disease Resistance
- Evolution, Molecular
- Female
- Gene Knock-In Techniques
- HEK293 Cells
- Humans
- Immunoglobulins -- genetics
- Membrane Proteins -- chemistry
- Mice
- Mice, Inbred C57BL
- Molecular Docking Simulation
- NIH 3T3 Cells
- Protein Domains
- Receptors, Virus -- chemistry
- Vero Cells
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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