Inhibition of protein synthesis by a Vero toxin (VT2 or Shiga-like toxin II) produced by Escherichia coli O157:H7 at the level of elongation factor 1-dependent aminoacyl-tRNA binding to ribosomes. [electronic resource]
Producer: 19890126Description: 127-35 p. digitalISSN:- 0882-4010
- Animals
- Bacterial Toxins -- pharmacology
- Cell-Free System
- Centrifugation, Density Gradient
- Escherichia coli -- pathogenicity
- GTP Phosphohydrolase-Linked Elongation Factors -- metabolism
- Globins -- biosynthesis
- Peptide Biosynthesis
- Peptide Elongation Factor 1
- Peptide Elongation Factor 2
- Peptide Elongation Factors -- antagonists & inhibitors
- Peptides
- Protein Binding
- Protein Synthesis Inhibitors
- RNA, Transfer, Amino Acid-Specific -- metabolism
- Rabbits
- Rats
- Ribonucleoproteins -- antagonists & inhibitors
- Ribosomes -- drug effects
- Shiga Toxin 2
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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