Positive Effects of a Young Systemic Environment and High Growth Differentiation Factor 11 Levels on Chondrocyte Proliferation and Cartilage Matrix Synthesis in Old Mice. [electronic resource]
Producer: 20201005Description: 1123-1133 p. digitalISSN:- 2326-5205
- Adolescent
- Aged
- Aging -- genetics
- Animals
- Arthroplasty, Replacement, Knee
- Bone Morphogenetic Proteins -- metabolism
- Cartilage, Articular -- drug effects
- Cell Proliferation -- drug effects
- Chondrocytes -- drug effects
- Collagen Type II -- drug effects
- Collagen Type X -- drug effects
- Core Binding Factor Alpha 1 Subunit -- drug effects
- Extracellular Matrix -- drug effects
- Female
- Growth Differentiation Factors -- metabolism
- Humans
- In Vitro Techniques
- Knee Joint
- Male
- Matrix Metalloproteinase 13 -- drug effects
- Mice
- Osteoarthritis, Knee -- genetics
- Parabiosis
- Phosphorylation
- RNA, Messenger -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction
- SOX9 Transcription Factor -- drug effects
- Smad2 Protein -- drug effects
- Smad3 Protein -- drug effects
- Stifle
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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