Viperin, through its radical-SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication. [electronic resource]
Producer: 20210505Description: 1624-1630 p. digitalISSN:- 1873-3468
- Antiviral Agents -- metabolism
- Cell Respiration
- Cytidine Triphosphate -- metabolism
- Humans
- Inhibitory Concentration 50
- Mitochondria -- drug effects
- Nucleotides -- metabolism
- Oxidoreductases Acting on CH-CH Group Donors
- Proteins -- metabolism
- Uridine Triphosphate -- metabolism
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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