Hydrodynamics-based liver transfection achieves gene silencing of CB1 using short hairpin RNA plasmid in cirrhotic rats. [electronic resource]
Producer: 20200504Description: e0228729 p. digitalISSN:- 1932-6203
- Actins -- genetics
- Alanine Transaminase -- blood
- Animals
- Aspartate Aminotransferases -- blood
- Brain -- metabolism
- Cells, Cultured
- Disease Models, Animal
- Gene Silencing
- Hepatic Stellate Cells -- cytology
- Hydrodynamics
- Liver -- metabolism
- Liver Cirrhosis -- pathology
- Male
- Plasmids -- metabolism
- RNA, Small Interfering -- administration & dosage
- Rats
- Rats, Wistar
- Receptor, Cannabinoid, CB1 -- antagonists & inhibitors
- Transfection
- Transforming Growth Factor beta1 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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