PI3K/mTORC1/2 inhibitor PQR309 inhibits proliferation and induces apoptosis in human glioblastoma cells. [electronic resource]
Producer: 20200923Description: 773-782 p. digitalISSN:- 1791-2431
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Glioblastoma -- drug therapy
- Humans
- Mechanistic Target of Rapamycin Complex 1 -- antagonists & inhibitors
- Mechanistic Target of Rapamycin Complex 2 -- antagonists & inhibitors
- Neoplasm Invasiveness -- genetics
- Neoplasm Proteins -- genetics
- Phosphatidylinositol 3-Kinases -- drug effects
- Phosphoinositide-3 Kinase Inhibitors -- pharmacology
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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