Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway. [electronic resource]
Producer: 20200810Description: 105604 p. digitalISSN:- 1879-1220
- Androstanes -- metabolism
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Cell Proliferation
- DNA Fragmentation
- Dogs
- Hep G2 Cells
- Humans
- Inhibitory Concentration 50
- Liver -- metabolism
- Liver Neoplasms -- drug therapy
- Madin Darby Canine Kidney Cells
- Molecular Docking Simulation
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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