YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. [electronic resource]
Producer: 20200408Description: 507 p. digitalISSN:- 2041-1723
- Adaptor Proteins, Signal Transducing -- metabolism
- Alzheimer Disease -- cerebrospinal fluid
- Amyloid beta-Peptides -- metabolism
- Animals
- Cell Cycle Proteins -- metabolism
- Cell Nucleus -- metabolism
- Cognitive Dysfunction -- cerebrospinal fluid
- Computer Simulation
- Disease Models, Animal
- Endoplasmic Reticulum -- pathology
- Female
- HMGB1 Protein -- cerebrospinal fluid
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Lysophospholipids -- metabolism
- Male
- Mice, Transgenic
- Necrosis
- Neurons -- metabolism
- Signal Transduction
- Sphingosine -- analogs & derivatives
- Time-Lapse Imaging
- Transcription Factors -- metabolism
- YAP-Signaling Proteins
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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